Anti-depressants are psychotropic drugs used primarily to treat depression. Anti-depressants can improve general mood, reduce or relieve depression, lethargy, apathy, anxiety and emotional stress, increase mental alertness, normalize sleep providing long-lasting effect. All anti-depressants are divided into 3 groups: selective serotonin reuptake inhibitors (SSRIs) tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs). MAOIs are helpful in mood management, whereas TCAs have more calming effect, SSRIs are the ones almost deprived side effects. Anti-Depressants can also facilitate treatment of such mental disorders as anxiety, insomnia, and prevent from panic attacks.